--- title: High-Throughput Genotyping Case Study | GENEWIZ from Azenta description: This case study focuses on a collaboration between GENEWIZ from Azenta Life Sciences and a large pharmaceutical client to develop a new approach for screening engineered cell lines. --- [Skip to content](https://web.genewiz.com/case-study/high-throughput-genotyping#main-content) [![GENEWIZ](https://web.genewiz.com/hubfs/GENEWIZ%20Brand%20Assets/GENEWIZ%20Logos/2025-04%20Current%20GENEWIZ%20Logos/GENEWIZ_Full-Color_Logo_PublicWeb_200x63.svg "GENEWIZ")](https://www.genewiz.com/) English # High-Throughput Genotyping Case Study CASE STUDY ## Rapid, Scalable, and Ultra-Sensitive Validation of Allele-Specific Gene Editing Events with genoTYPER-NEXT™ This case study highlights a collaboration between **GENEWIZ from Azenta Life Sciences** and a large pharmaceutical company to develop a more effective and scalable approach for **screening engineered cell lines** using an **automated, interactive, NGS-based genotyping platform**. This powerful solution enables **high-resolution identification of genome editing outcomes**, including **mono-allelic, homozygous, and heterozygous bi-allelic gene editing events**, while significantly reducing manual data handling and interpretation time. ### What you'll learn - How **NGS-based genoTYPER-NEXT™** streamlines **high-throughput screening of engineered cell lines** - The limitations of traditional mutation detection and Sanger-based workflows for **bi-allelic gene editing validation** - How **automated, interactive data visualization** simplifies interpretation of **CRISPR, TALEN, and ZFN editing outcomes** - The advantages of **ultra-sensitive detection** for identifying rare and complex **INDEL mutation patterns** ![genoTYPER-NEXT Cover Thumbnail](https://web.genewiz.com/hs-fs/hubfs/genoTYPER-NEXT%20Cover%20Thumbnail.png?width=479&height=620&name=genoTYPER-NEXT%20Cover%20Thumbnail.png "genoTYPER-NEXT Cover Thumbnail") ## Download Case Study ## Related Services [CRISPR Validation](https://www.genewiz.com/public/services/next-generation-sequencing/high-throughput-genotyping) NGS-based validation of CRISPR editing efficiency and specificity. [Amplicon Sequencing Services](https://www.genewiz.com/public/services/next-generation-sequencing/amplicon-sequencing-services) Targeted sequencing of specific genomic regions with high sensitivity. [CRISPR gRNA Synthesis](https://www.genewiz.com/public/services/gene-synthesis/crispr-construct-synthesis) Custom guide RNA production for precise genome editing.