Recombinant Antibody Production Case Study

High-Throughput, Mid-Scale Production of Recombinant Antibodies

Recombinant antibody production is integral to most therapeutic antibody workflows. After screening in vivo or in vitro, leads undergo optimization and, if necessary, humanization. Engineering of antibody sequences to improve binding, specificity, stability, and function requires the generation and testing of the purified protein. Transient antibody expression is typically used for research applications as it enables fast and parallel production without the generation of stable cell lines. Here, we discuss how Azenta's recombinant antibody production workflow helped streamline a biopharmaceutical client's biologics research project at milligram scale.