Single-Cell RNA-Seq Analysis Identifies Rare Drug-Resistant Cancer Stem Cells
CASE STUDY
Single-Cell RNA-Seq Analysis Identifies Rare Drug-Resistant Cancer Stem Cells
Cell populations are rarely homogeneous and synchronized in their characteristics. Standard RNA-Seq approaches are limited to reporting general expression levels thus omitting minor subpopulation profiles. This study highlights new single cell RNA-sequencing capabilities for identifying rare cells, characterizing their transcriptomes, and discovering potential biomarkers.
This case study discusses:
- Rare cancer cell detection
- 10X Genomics Chromium™ technology
- Single-cell RNA sequencing
- Expression profiles for low frequency cell subpopulations
