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GENEWIZ offers a wide range of services to support research in oncology and genetic disorders. From the latest next generation sequencing (NGS) technologies to traditional polymorphism detection via Sanger-based services, our genomic solutions for cancer research can be used to elucidate mechanisms of cancer, drive therapeutic target discovery, enhance biomarker discovery, and stratify patients in clinical trials. Find out more about our oncology-based solutions below.

 

NEXT GENERATION SEQUENCING

 

rna

RNA-SEQ

Single-Cell RNA Sequencing
Single-Cell RNA Sequencing is able to unveil misregulation of critical pathways in tumor (and other) samples typically missed by standard bulk RNA_seq.

We also offer....

Standard RNA Sequencing

Ultra-Low RNA Sequencing

Isoform Sequencing

 

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GENOME AND TARGETED

Structural Variant Detection (>1kb)
PacBio® long-read sequencing technology is optimal for the detection of large genomic rearrangements, which have been shown to drive tumor development.

We also offer....

Illumina®-based Whole Genome Seq

Exome Sequencing

Customized Oncology Panels

 

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EPIGENOMICS

Whole Genome Bisulfite Sequencing
Whole genome bisulfite sequencing (WGBS) provides robust, global detection of 5-methylcytosine (5mC), a common form of epigenetic regulation in cancer.

We also offer....

ChIP-Seq

ATAC-Seq


 

SANGER-BASED SOLUTIONS

 

sanger

STANDALONE SANGER

Same Day Sanger Sequencing
Same day Sanger sequencing can be used to promptly confirm allelic variants in tumor samples originally identified by next generation sequencing techniques.

We also offer....

Direct Colony Sequencing

Clinical Sanger Sequencing

 

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FULL SERVICE

Custom Sanger Assays
Our Mutation Analysis bundle service includes pre-developed assays for oncogenes, PCR amplification, and data analysis, allowing researchers to explore or confirm mutations linked to oncogenesis.

We also offer....

Pre-Developed Oncogene Assay

GLP-Level Assays


 

SYNTHETIC DNA SOLUTIONS

 

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SYNTHETIC DNA LIBRARIES

Synthetic DNA Libraries
Trimer-controlled libraries eliminate the introduction of unwanted codons and frame-shift mutations to achieve greater control over your library.

We also offer....

Alanine Scanning Library

Variant Synthesis Library

Site-directed Mutagenesis

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LINEAR DNA FRAGMENTS

Single Stranded DNA
Single-Stranded DNA donor templates can be utilized for CRISPR mediated gene knock-ins of oncogenes to generate transgenic mouse models for cancer research.

We also offer....

DNA Fragments

Modified Oligos

site-directed

PLASMID CONSTRUCTS

Synthetic Genes
Synthetic genes are being utilized in the design and synthesis of chimeric antigen receptors (CAR) that are specifically engineered to elicit an antitumor response. 

We also offer....

Mutagenesis

CRISPR gRNA Constructs

Large Scale DNA Preparations

 

 


 

The GENEWIZ Difference 

 

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Ph.D. experts are available to discuss your project

877-436-3949

Next Generation Sequencing ext. 1 ngs@genewiz.com
Sanger Sequencing ext. 2 dnaseq@genewiz.com
Synthetic DNA Solutions ext. 3 pm@genewiz.com
Molecular Genetics ext. 3350 molgen@genewiz.com
GLP-Compliant Services ext. 3350 regulatory@genewiz.com