GENEWIZ offers a wide range of services to support research in oncology and genetic disorders. From the latest next generation sequencing (NGS) technologies to traditional polymorphism detection via Sanger-based services, our genomic solutions for cancer research can be used to elucidate mechanisms of cancer, drive therapeutic target discovery, enhance biomarker discovery, and stratify patients in clinical trials. Find out more about our oncology-based solutions below.
Single-Cell RNA Sequencing
Single-Cell RNA Sequencing is able to unveil misregulation of critical pathways in tumor (and other) samples typically missed by standard bulk RNA_seq.
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Structural Variant Detection (>1kb)
PacBio® long-read sequencing technology is optimal for the detection of large genomic rearrangements, which have been shown to drive tumor development.
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Illumina®-based Whole Genome Seq
Whole Genome Bisulfite Sequencing
Whole genome bisulfite sequencing (WGBS) provides robust, global detection of 5-methylcytosine (5mC), a common form of epigenetic regulation in cancer.
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Same Day Sanger Sequencing
Same day Sanger sequencing can be used to promptly confirm allelic variants in tumor samples originally identified by next generation sequencing techniques.
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Custom Sanger Assays
Our Mutation Analysis bundle service includes pre-developed assays for oncogenes, PCR amplification, and data analysis, allowing researchers to explore or confirm mutations linked to oncogenesis.
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Synthetic DNA Libraries
Trimer-controlled libraries eliminate the introduction of unwanted codons and frame-shift mutations to achieve greater control over your library.
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Single Stranded DNA
Single-Stranded DNA donor templates can be utilized for CRISPR mediated gene knock-ins of oncogenes to generate transgenic mouse models for cancer research.
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Synthetic Genes
Synthetic genes are being utilized in the design and synthesis of chimeric antigen receptors (CAR) that are specifically engineered to elicit an antitumor response.
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The GENEWIZ Difference
Next Generation Sequencing | ext. 1 | ngs@genewiz.com |
Sanger Sequencing | ext. 2 | dnaseq@genewiz.com |
Synthetic DNA Solutions | ext. 3 | pm@genewiz.com |
Molecular Genetics | ext. 3350 | molgen@genewiz.com |
GLP-Compliant Services | ext. 3350 | regulatory@genewiz.com |
115 Corporate Boulevard, South Plainfield, NJ 07080 |
+1-908-222-0711 | +1-908-333-4511
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