High-Resolution Spatial Profiling and Biomarker Discovery by Visium HD
High-Resolution Spatial Profiling and Biomarker Discovery with Visium HD
Despite significant advancements brought by traditional RNA sequencing methods, important limitations remain when it comes to spatial gene expression analysis. Bulk RNA-seq lacks spatial context, while single-cell RNA-seq sacrifices tissue architecture, both creating gaps in biological interpretation. Here, we explore how the 10X Genomics Visium HD® spatial transcriptomics platform bridges the gap between histology and gene expression profiling, enabling high-resolution spatial profiling, precise biomarker discovery, and detailed cellular mapping within complex tissues. This approach supports deeper biological insight across oncology, immunology, and developmental biology research.
What You'll Learn
- Learn how 10X Genomics Visium HD spatial transcriptomics enables comprehensive spatial characterization of tissues while preserving cellular context.
- Explore a qualification study demonstrating high specificity, sensitivity, and consistency in cell type identification across technical replicates.
- Understand how high-resolution gene expression mapping improves the identification of spatially specific biomarkers, providing deeper insight into tumor microenvironments, immune cell localization, and developmental processes.
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