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A Comprehensive Guide to Using Adeno-Associated Virus (AAV) Vectors in Gene Therapy

 
On-Demand Webinar
 
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About the webinar

Adeno-associated virus (AAV) vectors have become an ideal vehicle for in vivo gene therapy due to their efficiency and safety in humans. However, there are many challenges to overcome during the AAV production process for rapid drug development.

Led by Andrea O'Hara, Ph.D., this workshop will help you understand the AAV workflow by covering AAV lab and bioinformatics analysis processes. Starting with upstream development, we review the gene synthesis, AAV plasmid preparation, and sequencing options available for AAV production and validation. We then discuss downstream analysis of the final packaged product to confirm purity, clonality, and fidelity.

 

What you'll learn about

  • How to optimize AAV plasmid preparation
  • Best practices to address unstable sequencing
  • Solutions for storing and indexing AAV products
  • Selection of purity and fidelity assays
  • Bioinformatics tools for interpreting complex data
  • GLP sequencing confirmation solutions

 

Presenters and Roundtable Experts

Andrea O'Hara, Ph.D.
Strategic Technical Specialist
Azenta Life Sciences

Elizabeth Louie, Ph.D.
Supervisor
Azenta Life Sciences

Xiangying (Candy) Mao, Ph.D.
Team Lead, Bioinformatics Scientist
Azenta Life Sciences

Ming Yang, Ph.D.
Business Process Manager
Azenta Life Sciences

Liz Tseng, Ph.D.
Associate Director
PacBio

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